Atlantic salmon possesses two clusters of type I interferon receptor genes on different chromosomes, which allows for a larger repertoire of interferon receptors than in zebrafish and mammals.

@article{Sun2014AtlanticSP,
  title={Atlantic salmon possesses two clusters of type I interferon receptor genes on different chromosomes, which allows for a larger repertoire of interferon receptors than in zebrafish and mammals.},
  author={Baojian Sun and Linn Greiner-Tollersrud and Ben F. Koop and B\orre Robertsen},
  journal={Developmental and comparative immunology},
  year={2014},
  volume={47 2},
  pages={275-86}
}
Mammalian type I interferons (IFNs) signal through a receptor composed of the IFNAR1 and IFNAR2 chains. In zebrafish two-cysteine IFNs utilize a receptor composed of CRFB1 and CRFB5, while four-cysteine IFNs signal through a receptor formed by CRFB2 and CRFB5. In the present work two CRFB clusters were identified in different chromosomes of Atlantic salmon… CONTINUE READING