Atherosclerosis measured by B-mode ultrasonography: effect of statin therapy on disease progression.

@article{Kastelein2004AtherosclerosisMB,
  title={Atherosclerosis measured by B-mode ultrasonography: effect of statin therapy on disease progression.},
  author={John J. P. Kastelein and Eric de Groot and Raaj R Sankatsing},
  journal={The American journal of medicine},
  year={2004},
  volume={116 Suppl 6A},
  pages={31S-36S}
}
Changes in intima-media thickness (IMT) and arterial lumen diameter-as measured by B-mode high-resolution ultrasonography and quantitative coronary angiography, respectively-are currently the only surrogate markers for progression of atherosclerotic disease recognized by regulatory authorities in the United States and Europe. Because atherosclerosis is a disease of the arterial wall, the ability of B-mode ultrasonography to provide visualization of IMT offers significant advantages over… CONTINUE READING
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