Atherosclerosis: the emerging role of inflammation and the CD40-CD40 ligand system.

  title={Atherosclerosis: the emerging role of inflammation and the CD40-CD40 ligand system.},
  author={Richard P Phipps},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={97 13},
  • Richard P Phipps
  • Published 2000 in
    Proceedings of the National Academy of Sciences…
A therosclerosis is a principal cause of death in the Westernized world. Previously, it was thought to be a disease primarily involving lipid accumulation in the arterial walls. The inflammatory cells found at the sites of fatty streaks as well as in the more advanced lesions were not considered to be principally responsible for the disease. A different view of atherosclerosis has emerged subsequently. Current concepts of this disease include involvement of the immune system and chronic… CONTINUE READING
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