Atherosclerosis, dementia, and Alzheimer disease in the Baltimore Longitudinal Study of Aging cohort.

@article{Dolan2010AtherosclerosisDA,
  title={Atherosclerosis, dementia, and Alzheimer disease in the Baltimore Longitudinal Study of Aging cohort.},
  author={Hillary Dolan and Barbara J. Crain and Juan C Troncoso and Susan M. Resnick and Alan B. Zonderman and Richard J Obrien},
  journal={Annals of neurology},
  year={2010},
  volume={68 2},
  pages={231-40}
}
OBJECTIVE Although it is now accepted that asymptomatic cerebral infarcts are an important cause of dementia in the elderly, the relationship between atherosclerosis per se and dementia is controversial. Specifically, it is unclear whether atherosclerosis can cause the neuritic plaques and neurofibrillary tangles that define Alzheimer neuropathology and whether atherosclerosis, a potentially reversible risk factor, can influence cognition independent of brain infarcts. METHODS We examined the… CONTINUE READING

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