Atherosclerosis, autoimmunity, and systemic lupus erythematosus.

Abstract

Atherosclerosis can be considered a chronic inflammatory condition of the vessel wall. Fatty streaks, the earliest morphological lesions of atherosclerosis, are caused by lipids (primarily of cholesteryl esters) accumulated within the macrophages (foam cells) and smooth muscle cells in the intimal layer. These lesions progress into atherosclerotic plaques… (More)

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