Atg5 siRNA inhibits autophagy and enhances norcantharidin-induced apoptosis in hepatocellular carcinoma.

Abstract

Cantharidin is a terpenoid isolated from Chinese blister beetles, and norcantharidin (NCTD) is a demethylated analog of cantharidin. It has been reported that cantharidin and norcantharidin have anticancer activities. Growing evidence suggests that inhibiting autophagy can induce apoptosis in the human hepatoma cell line HepG2. The objective of the present… (More)
DOI: 10.3892/ijo.2015.3103

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@article{Xiong2015Atg5SI, title={Atg5 siRNA inhibits autophagy and enhances norcantharidin-induced apoptosis in hepatocellular carcinoma.}, author={Xuanxuan Xiong and Mingbo Wu and Haiyan Zhang and Jin Li and Bo Lu and Yonggao Guo and Tian Zhou and Hao Guo and Rui Peng and Xiangcheng Li and Qingzhong Tian and Yun Wang}, journal={International journal of oncology}, year={2015}, volume={47 4}, pages={1321-8} }