Atg37 regulates the assembly of the pexophagic receptor protein complex.

@article{Nazarko2014Atg37RT,
  title={Atg37 regulates the assembly of the pexophagic receptor protein complex.},
  author={Taras Y. Nazarko},
  journal={Autophagy},
  year={2014},
  volume={10 7},
  pages={1348-9}
}
Like other selective autophagy pathways, the selective autophagy of peroxisomes, pexophagy, is controlled by receptor protein complexes (RPCs). The pexophagic RPC in Pichia pastoris consists of several proteins: Pex3 and Pex14 ligands in the peroxisomal membrane, Atg30 receptor, Atg11, and Atg17 scaffolds, and the phagophore protein Atg8. Recently, we identified a new component of the pexophagic RPC, Atg37, which is involved in the assembly of this complex. Atg37 is an integral peroxisomal… CONTINUE READING
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