Ataxia-telangiectasia mutated (ATM) genetic variant in Italian centenarians

  title={Ataxia-telangiectasia mutated (ATM) genetic variant in Italian centenarians},
  author={Irene Piaceri and Silvia Bagnoli and Andrea Tedde and Sandro Sorbi and Benedetta Nacmias},
  journal={Neurological Sciences},
Lifespan is attributable to genetic factors and some studies have attempted to identify putative genes implicated in human longevity. Several genetic loci have been associated with longevity, but some of these are not replicable, probably due to the vast differences among ethnicities. We analyzed in 128 Italian long-lived individuals and 150 unrelated healthy subjects, the recently reported association between rs189037 in the ataxia-telangiectasia mutated gene promoter and longevity in Chinese… CONTINUE READING