At the intersection of non-coding transcription, DNA repair, chromatin structure, and cellular senescence

@inproceedings{Ohsawa2013AtTI,
  title={At the intersection of non-coding transcription, DNA repair, chromatin structure, and cellular senescence},
  author={Ryosuke Ohsawa and Ja-Hwan Seol and Jessica K Tyler},
  booktitle={Front. Genet.},
  year={2013}
}
It is well accepted that non-coding RNAs play a critical role in regulating gene expression. Recent paradigm-setting studies are now revealing that non-coding RNAs, other than microRNAs, also play intriguing roles in the maintenance of chromatin structure, in the DNA damage response, and in adult human stem cell aging. In this review, we will discuss the complex inter-dependent relationships among non-coding RNA transcription, maintenance of genomic stability, chromatin structure, and adult… CONTINUE READING
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