At the crossroads of vaginal health and disease, the genome sequence of Lactobacillus iners AB-1.

@article{Macklaim2011AtTC,
  title={At the crossroads of vaginal health and disease, the genome sequence of Lactobacillus iners AB-1.},
  author={Jean M. Macklaim and Gregory B. Gloor and Kingsley C. Anukam and Sarah Cribby and Gregor Reid},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2011},
  volume={108 Suppl 1},
  pages={4688-95}
}
Lactobacilli have long been regarded as important constituents of the healthy human vagina. Lactobacillus iners is the most frequently detected bacterial species in the vagina, but little is known about its characteristics. We report a description of the whole-genome sequence of L. iners AB-1 along with comparative analysis of published genomes of closely related strains of lactobacilli. The genome is the smallest Lactobacillus reported to date, with a 1.3-Mbp single chromosome. The genome… CONTINUE READING
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