At the bench: understanding group 2 innate lymphoid cells in disease.

Abstract

The conventional paradigm of type 2 inflammatory responses is characterized by activation of CD4(+) Th2 cells that produce IL-4, IL-5, and IL-13, resulting in tissue eosinophil infiltration, mucus metaplasia, AHR, and IgE production. However, the recent discovery of ILC2s in mice and humans has brought forth a novel pathway in type 2 immunity that may work… (More)
DOI: 10.1189/jlb.5BT0814-374R

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Cite this paper

@article{Doherty2015AtTB, title={At the bench: understanding group 2 innate lymphoid cells in disease.}, author={Taylor A. Doherty}, journal={Journal of leukocyte biology}, year={2015}, volume={97 3}, pages={455-67} }