Asynchronous replication of alleles in genomes carrying a microdeletion.

Abstract

BACKGROUND While most allelic pairs of DNA replicate synchronously during the S phase of the cell cycle, some genes normally replicate asynchronously, i.e., genes on the X chromosome and imprinted genes. The replication control mechanism is unknown but was shown to be impaired in malignancies and chromosomal trisomies where replication pattern becomes… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.