Asymptomatic small fiber neuropathy in diabetes mellitus: investigations with intraepidermal nerve fiber density, quantitative sensory testing and laser-evoked potentials

@article{Rag2011AsymptomaticSF,
  title={Asymptomatic small fiber neuropathy in diabetes mellitus: investigations with intraepidermal nerve fiber density, quantitative sensory testing and laser-evoked potentials},
  author={Michael Rag{\'e} and Nathalie Van Acker and Michiel W. M. Knaapen and Maarten Timmers and Johannes Rolf Streffer and Michel P Hermans and Christian Jean-Marie Sindic and Theo Meert and Leon H Plaghki},
  journal={Journal of Neurology},
  year={2011},
  volume={258},
  pages={1852-1864}
}
This study aimed at evaluating the performance of a battery of morphological and functional tests for the assessment of small nerve fiber loss in asymptomatic diabetic neuropathy (DNP). Patients diagnosed for ≥10 years with type 1 (n = 10) or type 2 (n = 13) diabetes mellitus (DM) without conventional symptoms or signs of DNP were recruited and compared with healthy controls (n = 18) and patients with overt DNP (n = 5). Intraepidermal nerve fiber density (IENFd) was measured with PGP9.5… CONTINUE READING

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