Asymptomatic infection of adult volunteers with a temperature sensitive mutant of Mycoplasma pneumoniae.

Abstract

Temperature sensitive mutants of Mycoplasma pneumoniae were developed with the expectation that their temperature sensitive defects would restrict replication in vivo at the temperature of the lower respiratory tract, whereas such defects would not seriously impair replication in the cooler environment of the upper respiratory passages. One such ts mutant… (More)

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