Asymmetry between pushing and pulling for crawling cells.

  title={Asymmetry between pushing and pulling for crawling cells.},
  author={Pierre Recho and Lev Truskinovsky},
  journal={Physical review. E, Statistical, nonlinear, and soft matter physics},
  volume={87 2},
  • P. Recho, L. Truskinovsky
  • Published 16 February 2013
  • Biology
  • Physical review. E, Statistical, nonlinear, and soft matter physics
Eukaryotic cells possess motility mechanisms allowing them not only to self-propel but also to exert forces on obstacles (to push) and to carry cargoes (to pull). To study the inherent asymmetry between active pushing and pulling we model a crawling acto-myosin cell extract as a one-dimensional layer of active gel subjected to external forces. We show that pushing is controlled by protrusion and that the macroscopic signature of the protrusion dominated motility mechanism is concavity of the… 
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