Asymmetry across species

@article{Jan1999AsymmetryAS,
  title={Asymmetry across species},
  author={Yuh Nung Jan and Lily Yeh Jan},
  journal={Nature Cell Biology},
  year={1999},
  volume={1},
  pages={E42-E44}
}
  • Y. JanL. Jan
  • Published 1 June 1999
  • Biology
  • Nature Cell Biology
In both worms and flies, asymmetric cell divisions involve the protein Bazooka/PAR-3, which is required for the asymmetric segregation of cell-fate determinants. However, differential distribution of a determinant between daughter cells may be achieved by different means in alternative developmental settings. 
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10 Citations
Background Citations
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10 Citations

Control of cell divisions in the nervous system: symmetry and asymmetry.

The identification in Drosophila of asymmetrically distributed fate determinants, adapter molecules, and polarity organizing molecules that participate in asymmetric neural progenitor divisions should provide points of entry for studying similar asymmetric divisions in vertebrates.

Zebrafish vasa RNA but Not Its Protein Is a Component of the Germ Plasm and Segregates Asymmetrically before Germline Specification

The asymmetric segregation of zebrafish vasa RNA is described, which distinguishes germ cell precursors from somatic cells in cleavage stage embryos, a process that precedes primordial germ cell proliferation and perinuclear localization of Vasa protein.

Steel Factor Regulates Cell Cycle Asymmetry

It is proposed that SLF/GM‐CSF synergy is, in part, due to a shift in proliferation pattern from a heterogeneous and asymmetric one to a more synchronous and symmetric pattern, thus contributing dramatically to the rapid expansion that accompanies SLF synergy observed in MO7e cells.

Bazooka is a permissive factor for the invasive behavior of discs large tumor cells in Drosophila ovarian follicular epithelia

It is shown here that wild-type bazooka function is required during cell invasion of epithelial follicle cells mutant for the tumor suppressor discs large, and clonal studies indicate that follicle cell Bazooka acts as a permissive factor duringcell invasion, possibly by stabilizing adhesion between the invading somatic cells and their substratum, the germline cells.

The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts

It is shown that the lethal giant larvae (lgl) and discs large (dlg) regulate basal protein targeting, but not apical complex formation or spindle orientation, in both embryonic and larval neuroblasts.

Mnb/Dyrk1A is transiently expressed and asymmetrically segregated in neural progenitor cells at the transition to neurogenic divisions.

It is proposed that Mnb defines a transition step between proliferating and neurogenic divisions of NEP cells, and is asymmetrically localized during the mitosis of cells and inherited by one of the sibling cells after division.

Multipotent Stem Cells in the Embryonic Nervous System

This chapter will focus on the properties of mammalian neural stem cells, which are multipotent stem cells that have an unlimited capacity to proliferate and self-renew but whose progeny are restricted to neural lineages.

Bionic asymmetry: from amiiform fish to undulating robotic fins

Similar to bionic non-smooth which has been successfully applied in anti-resistance and anti-adhesion, bionic asymmetry is also an inherent property of biological systems and is worth exploring for…

Eutacticity in Sea Urchin Evolution

Changes of regularity (eutacticity) in a macroevolutive and taxonomic level of sea urchins belonging to the Echinoidea class suggests a high degree ofregularity in the shape of these organisms through their evolution.

Gaining a better understanding of the mechanisms that govern normal cell motility and invasion is crucial for understanding development but may also contribute to understanding forms of aberrant cell invasion and migration of metastatic tumor

  • 2003

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