Asymmetric trimethine 3H-indocyanine dyes: efficient synthesis and protein labeling.

@article{Song2010AsymmetricT3,
  title={Asymmetric trimethine 3H-indocyanine dyes: efficient synthesis and protein labeling.},
  author={Fengling Song and Li Wang and Xiaoqiang Qiao and Bingshuai Wang and Shiguo Sun and Jiangli Fan and Lihua Zhang and Xiaojun Peng},
  journal={Organic \& biomolecular chemistry},
  year={2010},
  volume={8 19},
  pages={
          4249-51
        }
}
We present an efficient method to synthesize three new asymmetric trimethine cyanine dyes containing only one carboxylic acid group for bioconjugation. Two of them have better protein labeling performance than other conventional cyanine dyes due to their particular structure design. 
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