Asymmetric spiroacetalization catalysed by confined Brønsted acids

@article{ori2012AsymmetricSC,
  title={Asymmetric spiroacetalization catalysed by confined Br{\o}nsted acids},
  author={Ilija {\vC}ori{\'c} and Benjamin List},
  journal={Nature},
  year={2012},
  volume={483},
  pages={315-319}
}
Acetals are molecular substructures that contain two oxygen–carbon single bonds at the same carbon atom, and are used in cells to construct carbohydrates and numerous other molecules. A distinctive subgroup are spiroacetals, acetals joining two rings, which occur in a broad range of biologically active compounds, including small insect pheromones and more complex macrocycles. Despite numerous methods for the catalytic asymmetric formation of other commonly occurring stereocentres, there are few… Expand
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