Asymmetric inhibitory connections enhance directional selectivity in a three-layer simulation model of retinal networks.

@article{Koizumi2010AsymmetricIC,
  title={Asymmetric inhibitory connections enhance directional selectivity in a three-layer simulation model of retinal networks.},
  author={Amane Koizumi and Misako Takayasu and Hideki Takayasu},
  journal={Journal of integrative neuroscience},
  year={2010},
  volume={9 3},
  pages={337-50}
}
In this paper, we found that spatial and temporal asymmetricity of excitatory connections are able to generate directional selectivity which can be enhanced by asymmetrical inhibitory connections by reconstructing a hexagonally-arranged three-layered simulation model of retina by NEURON simulator. Asymmetric excitatory inputs to ganglion cells with randomly arborizing dendrites were able to generate weaker directional selectivity to moving stimuli whose speed was less than 10 μm/msec. By just… CONTINUE READING