Asymmetric hydrogenation of ketones with polymer-supported chiral 1,2-diphenylethylenediamine.

Abstract

[reaction: see text] A poly(ethylene glycol)-supported chiral diamine (PEG-2), in which the polymer is attached to the phenyl rings, has been synthesized and shown to be highly effective in asymmetric hydrogenation of unfunctionalized aromatic ketones with the possibility of reuse. PEG-2 can also serve as a chiral scaffold on which various immobilized chiral catalysts could be easily built.

Cite this paper

@article{Li2003AsymmetricHO, title={Asymmetric hydrogenation of ketones with polymer-supported chiral 1,2-diphenylethylenediamine.}, author={Xiaoguang Li and Weiping Chen and William P. Hems and Frank King and Jianliang Xiao}, journal={Organic letters}, year={2003}, volume={5 24}, pages={4559-61} }