Asymmetric division in mouse oocytes: with or without Mos

@article{Verlhac2000AsymmetricDI,
  title={Asymmetric division in mouse oocytes: with or without Mos},
  author={Marie-H{\'e}l{\`e}ne Verlhac and Christophe Lefebvre and Philippe Guillaud and Pascale Rassinier and B. Maro},
  journal={Current Biology},
  year={2000},
  volume={10},
  pages={1303-1306}
}
In both vertebrates and invertebrates, meiotic divisions in oocytes are typically asymmetric, resulting in the formation of a large oocyte and small polar bodies. The size difference between the daughter cells is usually a consequence of asymmetric positioning of the spindle before cytokinesis. Spindle movements are often related to interactions between the cell cortex and the spindle asters [1,2]. The spindles of mammalian oocytes are, however, typically devoid of astral microtubules, which… CONTINUE READING
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