Asymmetric dimethylarginine reference intervals determined with liquid chromatography-tandem mass spectrometry: results from the Framingham offspring cohort.

@article{Schwedhelm2009AsymmetricDR,
  title={Asymmetric dimethylarginine reference intervals determined with liquid chromatography-tandem mass spectrometry: results from the Framingham offspring cohort.},
  author={Edzard Schwedhelm and Vanessa Xanthakis and Renke Maas and Lisa Sullivan and Friedrich W. Schulze and Ulrich Riederer and Ralf A. Benndorf and Rainer H. Boeger and Ramachandran S. Vasan},
  journal={Clinical chemistry},
  year={2009},
  volume={55 8},
  pages={
          1539-45
        }
}
BACKGROUND Accumulating evidence links higher circulating asymmetric dimethylarginine (ADMA) to greater risk of cardiovascular disease (CVD). Relatively small differences in ADMA concentrations between healthy individuals and those with disease underscore the need to formulate reference intervals that may aid risk stratification of individuals. METHODS We formulated reference intervals for plasma ADMA concentrations using a community-based reference sample from the Framingham Offspring Study… CONTINUE READING
Highly Cited
This paper has 28 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 42 references

HPLC analysis of ADMA and other methylated L-arginine analogs in biological fluids.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences • 2007