Asymmetric dimethylarginine independently predicts fatal and nonfatal myocardial infarction and stroke in women: 24-year follow-up of the population study of women in Gothenburg.

@article{Leong2008AsymmetricDI,
  title={Asymmetric dimethylarginine independently predicts fatal and nonfatal myocardial infarction and stroke in women: 24-year follow-up of the population study of women in Gothenburg.},
  author={Tora Leong and Dimitri Edin Zylberstein and Ian Graham and Lauren Lissner and Deirdre Ward and Jane Fogarty and Calle Bengtsson and Cecilia Bj{\"o}rkelund and Dag Steinar Thelle},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2008},
  volume={28 5},
  pages={961-7}
}
OBJECTIVE Asymmetrical dimethylarginine (ADMA) reduces nitric oxide by inhibiting nitric oxide synthase is associated with cardiovascular disease (CVD). Our study examined the association of ADMA with CVD prospectively in a healthy population-based cohort of women. METHODS AND RESULTS We measured baseline ADMA of 880 women in the Population Study of Women in Gothenburg using high-performance liquid chromatography. After adjustment for traditional risk factors, creatinine clearance, and… CONTINUE READING

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