Asymmetric dimethylarginine enhances cardiovascular risk prediction in patients with chronic heart failure.

@article{Dckelmann2007AsymmetricDE,
  title={Asymmetric dimethylarginine enhances cardiovascular risk prediction in patients with chronic heart failure.},
  author={Christina D{\"u}ckelmann and Friedrich Mittermayer and Dominik Georg Haider and Johann Altenberger and J{\"o}rg Eichinger and Michael Wolzt},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2007},
  volume={27 9},
  pages={2037-42}
}
OBJECTIVE The purpose of this study was to investigate whether elevated asymmetrical dimethylorginine (ADMA) concentrations are associated with increased cardiovascular risk in chronic heart failure (HF) patients. METHODS AND RESULTS 253 patients with symptomatic chronic HF and impaired left ventricular function (median age 70 years, 202 males) were followed for a median of 14.2 months (interquartile range 6.8 to 21.2). ADMA and N-terminal pro-brain natriuretic peptide (NT-proBNP) were… CONTINUE READING