Asymmetric cell division: lessons from flies and worms.

  title={Asymmetric cell division: lessons from flies and worms.},
  author={Biao Lu and Lily Yeh Jan and Yuh Nung Jan},
  journal={Current opinion in genetics & development},
  volume={8 4},
Insights into the mechanisms of asymmetric cell division have recently been obtained from studies in genetically amenable systems such as Drosophila and Caenorhabditis elegans. These studies have emphasized the importance of cortically localized polarity organizing molecules, adapter molecules, and the actin cytoskeleton in controlling unequal segregation of cell-fate determinants and spindle orientation. The control of asymmetric cell divisions by Wnt signaling in C. elegans and Frizzled… CONTINUE READING

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