Asymmetric and symmetric dimethylarginine are associated with coronary artery lesions in Kawasaki disease.

@article{Huang2014AsymmetricAS,
  title={Asymmetric and symmetric dimethylarginine are associated with coronary artery lesions in Kawasaki disease.},
  author={Ying-Hsien Huang and You-Lin Tain and Chiu-Ping Lee and Ho-Chang Kuo},
  journal={The Journal of pediatrics},
  year={2014},
  volume={165 2},
  pages={295-9}
}
OBJECTIVE To determine whether 3 biomarkers, L-arginine, asymmetric dimethylarginine (ADMA), and symmetric dimethylarginine (SDMA), can predict outcomes in patients with Kawasaki disease (KD). STUDY DESIGN Plasma levels of L-arginine, ADMA, and SDMA were measured in 39 patients with KD and 27 febrile control patients. RESULTS Plasma L-arginine, ADMA, and SDMA levels were lower in patients with KD than in control patients before treatment with intravenous immunoglobulin (IVIG; P=.027, P<.001… CONTINUE READING