Asymmetric Synthesis of the Marine Hepatotoxin 7-Epicylindrospermopsin * *

Abstract

The cyanobacterial toxin cylindrospermopsin (1) was isolated as the principal hepatotoxin from Cylindrospermopsis raciborskii in 1992 after suspicion of its involvement in an outbreak of hepatoenteritis that hospitalized 150 people on Palm Island, Australia. It has since been isolated in Japan from Umezakia natans and in Israel from Aphazinomenon… (More)

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