Asymmetric Autoamplification in the Oxidative Kinetic Resolution of Secondary Benzylic Alcohols Catalyzed by Manganese Complexes

@article{Talsi2017AsymmetricAI,
  title={Asymmetric Autoamplification in the Oxidative Kinetic Resolution of Secondary Benzylic Alcohols Catalyzed by Manganese Complexes},
  author={Evgenii P. Talsi and Denis G. Samsonenko and Konstantin P. Bryliakov},
  journal={ChemCatChem},
  year={2017},
  volume={9}
}
Herein, chiral Mn–aminopyridine complexes have been shown to catalyze the oxidation of alkylarenes to enantiomerically enriched 1‐arylalkanols with hydrogen peroxide. The observed enantiomeric excess values result from the direct enantioselective benzylic C−H hydroxylation, accompanied by stereoconvergent oxidative kinetic resolution of the resulting alcohol. Testing several (S,S)‐bipyrrolidine derived Mn complexes has revealed a novel catalyst (6) that exhibits the best kinetic resolution in… 
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Catalytic Asymmetric C–H Oxidation with H2O2 and O2
  • K. Bryliakov
  • Chemistry, Biology
    Green Chemistry and Sustainable Technology
  • 2019
This chapter surveys the existing catalyst systems, either organocatalytic or metal-based, for the chemo- and stereoselective oxidation of C–H groups with the environmentally benign oxidants H2O2 and
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