Astrovirus gastroenteritis.

  title={Astrovirus gastroenteritis.},
  author={Douglas K. Mitchell},
  journal={The Pediatric infectious disease journal},
  volume={21 11},
  • D. Mitchell
  • Published 2002
  • Medicine, Biology
  • The Pediatric infectious disease journal
Acute infectious gastroenteritis is one of the major causes of death in the world (1). It also produces an enormous burden of disease-related morbidity. In the United States, mortality is limited but morbidity is substantial (1). It is only in the past two decades that viral agents of acute gastroenteritis have been discovered and defined for the first time and have joined bacteria and parasites as medically important pathogens. Indeed, it is now recognized that viruses cause approximately 30… 

The Immune Response to Astrovirus Infection

Current understanding of the immune response to astrovirus infection is summarized and some of the key questions that stem from these studies are highlighted.

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Intra- and Cross-Species Transmission of Astroviruses

The current understanding of astrovirus transmission, the factors that influence viral spread, and the potential for cross-species transmission are reviewed; the current gaps in knowledge and areas of future research are highlighted.

Characterizing a Murine Model for Astrovirus Using Viral Isolates from Persistently Infected Immunocompromised Mice

MuAstV represents a useful model for studying asymptomatic human infection and gaining insight into the astrovirus pathogenesis and immunity, and both virus strains elicited minimal pathology and a lack of sustained immunity.

Detection of Astrovirus in Premature Infants With Necrotizing Enterocolitis

It is demonstrated that HAstV may be associated with the development of NEC in a subgroup of patients and provides further evidence for the important role of gastrointestinal viral infections in this most common gastrointestinal emergency in premature infants.

Viral Etiology and Incidence of Acute Gastroenteritis in Young Children Attending Day-Care Centers

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Viral agents of gastroenteritis. Public health importance and outbreak management.

  • C. LebaronN. P. Furutan S. Monroe
  • Medicine
    MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports
  • 1990
Control measures for outbreaks of viral gastroenteritis should focus on the removal of an ongoing common source of infection (e.g., an ill food handler or the contamination of a water supply) and on the interruption of person-to-person transmission that can perpetuate an outbreak in a population after the common source has been removed.

Astroviruses as a cause of gastroenteritis in children.

Astroviruses were found in association with gastroenteritis more frequently than were enteric adenoviruses, and with nearly half the frequency of rotaviruses.

Astrovirus as a cause of gastroenteritis in Japan

Astrovirus is more commonly associated with childhood gastroenteritis than has been previously appreciated and it is suggested that further studies to examine the epidemiology and disease burden of this virus are needed.

Astroviruses as a cause of nosocomial outbreaks of infant diarrhea.

During a 16-month study period at a children's hospital, 32 children developed nosocomial gastroenteritis caused by astroviruses, and the attack rates ranged between 7 and 62% and were highest among children with underlying gastrointestinal diseases.

Outbreaks of astrovirus type 1 and rotavirus gastroenteritis in a geriatric in-patient population.

Astrovirus infection in volunteers

It was concluded that astrovirus causes a transmissible infection that is of low pathogenicity for adults and has been identified as the “W” agent.

Astrovirus associated gastroenteritis in a children's ward.

During an outbreak of gastroenteritis in a paediatric ward astroviruses were found in faeces from 17 to 27 symptomatic children and from four of 14 members of the staff with diarrhoea. No viruses

A large outbreak of acute gastroenteritis associated with astrovirus among students and teachers in Osaka, Japan.

Astrovirus, identified as the etiologic agent, was detected by direct electron microscopy in 10 of 38 fecal samples obtained from patients with diarrhea.

An outbreak of gastroenteritis in a home for the elderly associated with astrovirus type 1 and human calicivirus

An outbreak of gastroenteritis, which lasted for 22 days in a residential home for the elderly, was biphasic and affected 34/42 (80%) residents and 13/29 members of the staff.