Astrogliopathology in neurological, neurodevelopmental and psychiatric disorders

  title={Astrogliopathology in neurological, neurodevelopmental and psychiatric disorders},
  author={Alexei Verkhratsky and Vladimir Parpura},
  journal={Neurobiology of Disease},
Astroglial cells represent a main element in the maintenance of homeostasis and providing defense to the brain. Consequently, their dysfunction underlies many, if not all, neurological, neurodevelopmental and neuropsychiatric disorders. General astrogliopathy is evident in diametrically opposing morpho-functional changes in astrocytes, i.e. their hypertrophy along with reactivity or atrophy with asthenia. Neurological disorders with astroglial participation can be genetic, of which Alexander… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 34 extracted citations

Similar Papers

Loading similar papers…