Astroglial regulation of sleep homeostasis

@article{Frank2013AstroglialRO,
  title={Astroglial regulation of sleep homeostasis},
  author={Marcos Gabriel Frank},
  journal={Current Opinion in Neurobiology},
  year={2013},
  volume={23},
  pages={812-818}
}
Mammalian sleep is regulated by two distinct mechanisms. A circadian oscillator provides timing signals that organize sleep and wake across the 24 hour day. A homeostatic mechanism increases sleep drive and sleep amounts (or intensity) as a function of prior time awake. The cellular mechanisms of sleep homeostasis are poorly defined, but are thought to be primarily neuronal. According to one view, sleep homeostasis arises from interactions between subcortical neurons that register sleep… CONTINUE READING

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