Astroglial reaction during the early phase of acute lead toxicity in the adult rat brain.

@article{Struyska2001AstroglialRD,
  title={Astroglial reaction during the early phase of acute lead toxicity in the adult rat brain.},
  author={Lidia Strużyńska and Irena Bubko and Michał Walski and Urszula Rafałowska},
  journal={Toxicology},
  year={2001},
  volume={165 2-3},
  pages={121-31}
}
The developing nervous system is susceptible to lead (Pb) exposure but less is known about the effect of this toxic agent in adult rat brain. Since astrocytes serve as a cellular Pb deposition site, it is of importance to investigate the response of astroglial cells in the adult rat brain in a model of acute lead exposure (25 mg/kg b.w. of lead acetate, i.p. for 3 days). An increased immunoreactivity of glial fibrillary acidic protein (GFAP) on Western blots was noticeable in fractions of… CONTINUE READING
28 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

Similar Papers

Loading similar papers…