Astrocytoma and pineoblastoma arising sequentially in the fourth ventricle of the same patient. Case report and molecular analysis.

@article{Brockmeyer1997AstrocytomaAP,
  title={Astrocytoma and pineoblastoma arising sequentially in the fourth ventricle of the same patient. Case report and molecular analysis.},
  author={Douglas L. Brockmeyer and Marion L. Walker and Gary Thompson and Daniel W. Fults},
  journal={Pediatric neurosurgery},
  year={1997},
  volume={26 1},
  pages={36-40}
}
The sequential appearance of two different brain tumors in the same patient without intervening radiation or chemotherapy is a rare event, most often seen in hereditary cancer syndromes. We present one such case of sequential tumors, along with their molecular analysis. A 17-year-old male presented with a pilocytic astrocytoma arising in the fourth ventricle at the pontomedullary junction. Six and one half years later, a pineoblastoma was discovered in the fourth ventricle, rostral to the first… CONTINUE READING