Astrocytic regulation of cortical UP states.

  title={Astrocytic regulation of cortical UP states.},
  author={Kira Poskanzer and Rafael Yuste},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={108 45},
The synchronization of neuronal assemblies during cortical UP states has been implicated in computational and homeostatic processes, but the mechanisms by which this occurs remain unknown. To investigate potential roles of astrocytes in synchronizing cortical circuits, we electrically activated astrocytes while monitoring the activity of the surrounding network with electrophysiological recordings and calcium imaging. Stimulating a single astrocyte activates other astrocytes in the local… CONTINUE READING