Astrocytic calcium signaling: mechanism and implications for functional brain imaging.

@article{Wang2009AstrocyticCS,
  title={Astrocytic calcium signaling: mechanism and implications for functional brain imaging.},
  author={Xiaohai Wang and Takahiro Takano and Maiken Nedergaard},
  journal={Methods in molecular biology},
  year={2009},
  volume={489},
  pages={93-109}
}
Astrocytes are electrically non-excitable cells that, on a slow time scale of seconds, integrate synaptic transmission by dynamic increases in cytosolic Ca2+. A number of groups have recently shown that astrocytic Ca2+ signaling regulates vascular tones and that astrocytes play a central role in functional hyperemia by Ca2+ -dependent release of Prostaglandin E2 (PGE2). Astrocytes are, however, not simple detectors of excitatory transmission, since a number of neuromodulator and hormones… CONTINUE READING
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