Astrocytic and neuronal biochemical markers in the sera of subjects with diabetes mellitus.

@article{Hovsepyan2004AstrocyticAN,
  title={Astrocytic and neuronal biochemical markers in the sera of subjects with diabetes mellitus.},
  author={Meri R Hovsepyan and Michael J. Haas and Anna S. Boyajyan and Astghik A Guevorkyan and Ashot A Mamikonyan and Susan E. Myers and Arshag D Mooradian},
  journal={Neuroscience letters},
  year={2004},
  volume={369 3},
  pages={224-7}
}
To determine if clinical diabetes is associated with disruption of the blood-brain barrier (BBB) and/or brain injury, enzyme-linked immunoassays and Western blots were used to measure serum levels of S100B, NSE and their auto-antibodies in type 1 and type 2 diabetic subjects. Serum S100B concentrations in type 2 diabetic subjects, but not in type 1 diabetic subjects, were significantly lower than those found in healthy controls. There were no significant differences in serum NSE levels of… CONTINUE READING

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