Astrocyte sodium signaling and neuro-metabolic coupling in the brain.

  title={Astrocyte sodium signaling and neuro-metabolic coupling in the brain.},
  author={Christine R Rose and J Chatton},
At tripartite synapses, astrocytes undergo calcium signaling in response to release of neurotransmitters and this calcium signaling has been proposed to play a critical role in neuron-glia interaction. Recent work has now firmly established that, in addition, neuronal activity also evokes sodium transients in astrocytes, which can be local or global depending on the number of activated synapses and the duration of activity. Furthermore, astrocyte sodium signals can be transmitted to adjacent… CONTINUE READING
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