Astrocyte signaling in the presence of spatial inhomogeneities.

  title={Astrocyte signaling in the presence of spatial inhomogeneities.},
  author={Michail Stamatakis and Nikos V. Mantzaris},
  volume={17 3},
Astrocytes, a special type of glial cells, were considered to have just a supporting role in information processing in the brain. However, several recent studies have shown that they can be chemically stimulated by various neurotransmitters, such as ATP, and can generate Ca2+ and ATP waves, which can propagate over many cell lengths before being blocked. Although pathological conditions, such as spreading depression and epilepsy, have been linked to abnormal wave propagation in astrocytic… CONTINUE READING