Astrocyte function is modified by Alzheimer's disease-like pathology in aged mice.

@article{Peters2009AstrocyteFI,
  title={Astrocyte function is modified by Alzheimer's disease-like pathology in aged mice.},
  author={Oliver Peters and Carola G. Schipke and Andreas Philipps and Brigitte Haas and Ulrike Pannasch and Li Ping Wang and Bruno Benedetti and Ann E. Kingston and Helmut Kettenmann},
  journal={Journal of Alzheimer's disease : JAD},
  year={2009},
  volume={18 1},
  pages={177-89}
}
Alzheimer's disease (AD) may affect all cell types in the central nervous system. Astrocytes have rarely been investigated in the aged brain and the role of astrocytes in AD is poorly understood. In this study, we used acute brain slices from an amyloid-beta overexpressing double transgenic mouse line where astrocytes express the enhanced green fluorescent protein under the control of the glial fibrillary acidic protein promoter. Using the patch-clamp technique, we analyzed cell coupling and… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 30 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 44 references

Similar Papers

Loading similar papers…