Astrocyte expression of mRNA encoding cytokines IP‐10 and JE/MCP‐1 in experimental autoimmune encephalomyelitis

@article{Ransohoff1993AstrocyteEO,
  title={Astrocyte expression of mRNA encoding cytokines IP‐10 and JE/MCP‐1 in experimental autoimmune encephalomyelitis},
  author={R. Ransohoff and T. Hamilton and M. Tani and M. Stoler and H. E. Shick and J. Major and M. Estes and Dawn M. Thomas and V. Tuohy},
  journal={The FASEB Journal},
  year={1993},
  volume={7},
  pages={592 - 600}
}
Mononuclear leukocytes preferentially accumulate in the central nervous system (CNS) during the course of experimental autoimmune encephalomyelitis (EAE). To address factors that govern leukocyte trafficking in EAE, we monitored expression of nxRNAs encoding IP‐10 and JE/MCP‐1, which are members of a family of chemoattractant cytokines. A transient burst of IP‐10 and JE/MCP‐1 mRNA accumulation in the CNS occurred, in close relation to the onset of histologic and clinical disease. In situ… Expand
IFN-Inducible Protein 10/CXC Chemokine Ligand 10-Independent Induction of Experimental Autoimmune Encephalomyelitis1
Sequential expression of chemokines in experimental autoimmune neuritis
Chemokine expression in GKO mice (lacking interferon-gamma) with experimental autoimmune encephalomyelitis.
Chemokine expression in murine experimental allergic encephalomyelitis
Chemokines and chemokine receptors in inflammation of the nervous system: manifold roles and exquisite regulation
  • DeRen Huang, Yulong Han, +11 authors R. Ransohoff
  • Biology, Medicine
  • Immunological reviews
  • 2000
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 37 REFERENCES
The expression of a gamma interferon-induced protein (IP-10) in delayed immune responses in human skin
Expression of cytokine-like genes JE and KC is increased during renal ischemia.
  • R Safirstein, J. Megyesi, +4 authors M B Taubman
  • Medicine
  • The American journal of physiology
  • 1991
T‐lymphocyte entry into the central nervous system
Acute Experimental Allergic Encephalomyelitis in SJL/J Mice Induced by a Synthetic Peptide of Myelin Proteolipid Protein
Astrocytes of the brain synthesize interleukin 3-like factors.
...
1
2
3
4
...