Astrocyte-conditioned medium attenuates glutamate-induced apoptotic cell death in primary cultured spinal cord neurons of rats.

Abstract

OBJECTIVES To better understand the neuroprotective role of astrocytes in spinal cord injury (SCI), we investigated whether astrocyte-conditioned medium (ACM) can attenuate glutamate-induced apoptotic cell death in primary cultured spinal cord neurons. METHODS Spinal cord neurons were pretreated with ACM for 24 hours. Subsequently, they were exposed to… (More)
DOI: 10.1179/1743132815Y.0000000059

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