Astrocyte calcium signaling transforms cholinergic modulation to cortical plasticity in vivo.

@article{Takata2011AstrocyteCS,
  title={Astrocyte calcium signaling transforms cholinergic modulation to cortical plasticity in vivo.},
  author={Norio Takata and Tsuneko Mishima and Chihiro Hisatsune and Terumi Nagai and Etsuko Ebisui and Katsuhiko Mikoshiba and Hajime Hirase},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2011},
  volume={31 49},
  pages={18155-65}
}
Global brain state dynamics regulate plasticity in local cortical circuits, but the underlying cellular and molecular mechanisms are unclear. Here, we demonstrate that astrocyte Ca(2+) signaling provides a critical bridge between cholinergic activation, associated with attention and vigilance states, and somatosensory plasticity in mouse barrel cortex in… CONTINUE READING
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