Astrocyte calcium signaling: the third wave

@article{Bazargani2016AstrocyteCS,
  title={Astrocyte calcium signaling: the third wave},
  author={N Yaghubi Bazargani and David Attwell},
  journal={Nature Neuroscience},
  year={2016},
  volume={19},
  pages={182-189}
}
The discovery that transient elevations of calcium concentration occur in astrocytes, and release 'gliotransmitters' which act on neurons and vascular smooth muscle, led to the idea that astrocytes are powerful regulators of neuronal spiking, synaptic plasticity and brain blood flow. These findings were challenged by a second wave of reports that astrocyte calcium transients did not mediate functions attributed to gliotransmitters and were too slow to generate blood flow increases. Remarkably… Expand
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