Astrocyte-Mediated Neuronal Synchronization Properties Revealed by False Gliotransmitter Release

Abstract

Astrocytes spontaneously release glutamate (Glut) as a gliotransmitter (GT), resulting in the generation of extrasynaptic NMDAR-mediated slow inward currents (SICs) in neighboring neurons, which can increase local neuronal excitability. However, there is a deficit in our knowledge of the factors that control spontaneous astrocyte GT release and the extent… (More)
DOI: 10.1523/JNEUROSCI.2761-16.2017

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