Astrocyte–endothelial interactions at the blood–brain barrier

@article{Abbott2006AstrocyteendothelialIA,
  title={Astrocyte–endothelial interactions at the blood–brain barrier},
  author={N. Abbott and L. R{\"o}nnb{\"a}ck and E. Hansson},
  journal={Nature Reviews Neuroscience},
  year={2006},
  volume={7},
  pages={41-53}
}
  • N. Abbott, L. Rönnbäck, E. Hansson
  • Published 2006
  • Biology, Medicine
  • Nature Reviews Neuroscience
  • The blood–brain barrier, which is formed by the endothelial cells that line cerebral microvessels, has an important role in maintaining a precisely regulated microenvironment for reliable neuronal signalling. At present, there is great interest in the association of brain microvessels, astrocytes and neurons to form functional 'neurovascular units', and recent studies have highlighted the importance of brain endothelial cells in this modular organization. Here, we explore specific interactions… CONTINUE READING

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