Astragaloside IV improves the isoproterenol-induced vascular dysfunction via attenuating eNOS uncoupling-mediated oxidative stress and inhibiting ROS-NF-κB pathways.

Abstract

OBJECTIVE Oxidative stress and inflammation are regarded as two important triggers of endothelial dysfunction and play pivotal role in progression of vascular damage associated with cardiac hypertrophy. Our previous studies demonstrated that astragaloside IV (AsIV) could protect against cardiac hypertrophy in rats induced by isoproterenol (Iso), but its… (More)
DOI: 10.1016/j.intimp.2016.02.009

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@article{Xu2016AstragalosideII, title={Astragaloside IV improves the isoproterenol-induced vascular dysfunction via attenuating eNOS uncoupling-mediated oxidative stress and inhibiting ROS-NF-κB pathways.}, author={Chonghua Xu and Futian Tang and Meili Lu and Jing Yang and Ronghui Han and Meng Mei and Jin Hu and Mingsheng Zhou and Hongxin Wang}, journal={International immunopharmacology}, year={2016}, volume={33}, pages={119-27} }