Astragaloside IV attenuates lipolysis and improves insulin resistance induced by TNFalpha in 3T3-L1 adipocytes.

@article{Jiang2008AstragalosideIA,
  title={Astragaloside IV attenuates lipolysis and improves insulin resistance induced by TNFalpha in 3T3-L1 adipocytes.},
  author={Boren Jiang and Ying Yang and Hua Jin and Wenbin Shang and Libin Zhou and Lei Qian and Mingdao Chen},
  journal={Phytotherapy research : PTR},
  year={2008},
  volume={22 11},
  pages={
          1434-9
        }
}
Increased circulating free fatty acid (FFA) concentrations have been demonstrated to potentially link obesity, insulin resistance and cardiovascular diseases. Astragaloside IV (AS-IV) is a saponin which is widely used in traditional Chinese medicine to treat type 2 diabetes and cardiovascular diseases. The purpose of the present study was to examine the effects of AS-IV on the lipolysis and insulin resistance induced by tumor necrosis factor-alpha (TNFalpha) in cultured 3T3-L1 adipocytes… CONTINUE READING
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