Asthma treatment outcome in adults is associated with rs9910408 in TBX21 gene

@inproceedings{Lopert2013AsthmaTO,
  title={Asthma treatment outcome in adults is associated with rs9910408 in TBX21 gene},
  author={Anton Lopert and M Rijavec and Mateja Žavbi and P Koro{\vs}ec and Matjaz Flezar},
  booktitle={Scientific reports},
  year={2013}
}
Inhaled corticosteroids (ICS) are one of the most commonly used asthma therapies and have highly variable treatment success. Polymorphisms in TBX21, a gene important for the biological action of corticosteroids, could be associated with treatment response in asthmatics. We genotyped for rs9910408 in TBX21 in 208 adult asthmatic patients, treated at least 3 years with ICS. Polymorphism rs9910408 was associated with response to ICS treatment. When treatment success was assessed by a decrease in… CONTINUE READING