Asthma: pathogenesis and novel drugs for treatment

  title={Asthma: pathogenesis and novel drugs for treatment},
  author={Jason T. Olin and Michael E. Wechsler},
  journal={BMJ : British Medical Journal},
  • J. OlinM. Wechsler
  • Published 24 November 2014
  • Medicine, Biology
  • BMJ : British Medical Journal
Asthma affects almost 20 million people in the United States and more than 300 million people worldwide. Of these, 10-15% have severe asthma, which is refractory to commonly available drugs. New drugs are needed because those that are currently available cannot control symptoms and exacerbations in all patients and can cause adverse reactions. In the past 10 years, there have been substantial advances in the understanding of asthma genetics, airway biology, and immune cell signaling. These… 


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