Asterosaponin 1, a cytostatic compound from the starfish Culcita novaeguineae, functions by inducing apoptosis in human glioblastoma U87MG cells

@article{Cheng2006Asterosaponin1A,
  title={Asterosaponin 1, a cytostatic compound from the starfish Culcita novaeguineae,
functions by inducing apoptosis in human glioblastoma U87MG cells},
  author={Guang Cheng and X. Zhang and H. Tang and Y. Zhang and W. Cao and D. Gao and X. Wang and B. Jin},
  journal={Journal of Neuro-Oncology},
  year={2006},
  volume={79},
  pages={235-241}
}
  • Guang Cheng, X. Zhang, +6 authors B. Jin
  • Published 2006
  • Biology, Medicine
  • Journal of Neuro-Oncology
    • SummaryMalignant glioblastoma is one of the most common malignant tumors in the neurological system. Asterosaponin 1, a new cytostatic agent from the starfish Culcita novaeguineae appear to exhibit various biological activities, including antitumor effect, but the function and mechanism of this new agent on glioblastoma cells has not previously been determined. In the present study, we investigated the proliferation change of human glioblastoma U87MG cells exposed to different concentrations (2… CONTINUE READING
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    References

    SHOWING 1-10 OF 34 REFERENCES
    Three new asterosaponins from the starfish Culcita novaeguineae and their bioactivity.
    • 32
    Methylene chloride fraction of Spatholobi Caulis induces apoptosis via caspase dependent pathway in U937 cells.
    • 13
    • PDF
    Asterosaponins from the starfish Culcita novaeguineae and their bioactivities.
    • 26
    PC-407 inhibited proliferation and induced apoptosis in human colon cancer SW-1116 cells
    • 2
    Curcumin, an antioxidant and anti-tumor promoter, induces apoptosis in human leukemia cells.
    • 404
    Multiparametric evaluation of apoptosis: effects of standard cytotoxic agents and the cyanoguanidine CHS 828.
    • 57
    • PDF
    Nonselective inhibition of proliferation of transformed and nontransformed cells by the anticancer agent curcumin (diferuloylmethane).
    • 51
    Chemosensitivity testing of primary human renal cell carcinoma by a tetrazolium based microculture assay (MTT)
    • 89
    Starfish saponins. 55. Isolation, structure elucidation, and biological activity of the steroid oligoglycosides from an Antarctic starfish of the family Asteriidae.
    • 46
    Bcl-2 mediated inhibition of erucylphosphocholine-induced apoptosis depends on its subcellular localisation.
    • 13